Biginelli Synthesis and Theoritical Study of Dihydropyrimidinone Compounds

نویسندگان

  • Mohammad Hosein Farjam Department of Chemistry , Firoozabad Branch, Islamic Azad University,Firoozabad, Iran
  • Ramin Rezaei Department of Chemistry , Firoozabad Branch, Islamic Azad University,Firoozabad, Iran
چکیده مقاله:

An effective one-pot synthesis of dihydropyrimidinonoes in solvent free conditions using CuCl2 as an inexpensive and readily available reagent through Biginelli condensation reaction of aldehyde derivatives, 1,3-dicarbonyl compounds and urea is described. Excellent yields, short reaction times for formation of the products and simple work-up are attractive features of this green protocol.

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منابع مشابه

Biginelli Synthesis and Theoritical Study of Dihydropyrimidinones

An effective one-pot synthesis of dihydropyrimidinonoes in solvent free conditions using CuCl2 as an inexpensive and readily available reagent through Biginelli condensation reaction of aldehyde derivatives, 1,3-dicarbonyl compounds and urea is described. Excellent yields, short reaction times for formation of the products and simple work-up are attractive features of this green protocol.

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Solvent-free One Pot Biginelli Method for Synthesis of new Dihydropyrimidinone compounds

An effective one-pot synthesis of dihydropyrimidinonoes in solvent free conditions using CuCl2 as an inexpensive and readily available reagent through Biginelli condensation reaction of aldehyde derivatives, 1,3-dicarbonyl compounds and urea is described. Excellent yields, short reaction times for formation of the products and simple work-up are attractive features of this green prot...

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عنوان ژورنال

دوره 8  شماره 1

صفحات  37- 43

تاریخ انتشار 2018-03-01

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